Terbutaline
This article covers many, but not all, of the possible side effects with terbutaline. Terbutaline babyTerbutaline risksProbably at least four classes of receptors exist for catecholamines. Ahlquist I ; originally divided the effects of catecholamines into two groups which he called alpha and beta. Subsequently it was found that the beta effects of catecholamines are generally associated with increases in cyclic AMP 2 ; . Lands et al. 3 ; subdivided the beta effects of catecholamines into beta, and betap based on structure-activity relationships for agonists. The beta: ! adrenoceptors are involved in bronchodilation and are preferentially activated by epinephrine, while norepinephrine has little activity. In contrast, norepinephrine and epinephrine are equipotent activators of betal adrenoceptors in heart and adipose tissue 4 ; . Compounds with bulky groups tertiary butyl ; on the amine carbon such as terbutaline and albuterol are preferential beta2 agonists, while a compound such as prenalterol is more active at betal sites 4 ; . Ariens et al. 5 ; suggested that the betal effects are due to norepinephrine released by sympathetic nerves, while beta2 effects are due to hormonal effects of epinephrine released by the adrenal medulla Fig. 1 ; . Alpha effects of catecholamines are also divided into alpha, and alpha2 types 6-9 ; . There appear to be s arate receptors for the alphal versus the alpha2 effects 9 ; , which is hardly surprising since they have different biochemical actions. Wikberg 7 ; and Fain and GarciaSAinz 8 ; suggested that alphal effects involve turnover of phosphatidylinositol and elevation of cytosol Ca2 + , while alpha2 effects involve inhibition of adenylate cyclase. However, in cells in which the level of cyclic AMP affects the cytosol Cap + pool or the biochemical actions of Ca2 + , there will be effects of alpha2activation on Ca2 + action Table 1 ; . These cells are subject to what might best be called antagonistic control since Cap + and cyclic AMP have opposite effects 10 ; . Smooth muscle is a and baclofen. Sodium chloride soln, 22 sodium phosphate sodium biphosphate, 17 SOMA, 12 somatropin, 15 sotalol, 9 spacer device, 22 spironolactone, 10 spironolactone hydrochlorothiazide, 10 SPORANOX, 5 starch packets, 19 stavudine, 6 succimer, 16 sucralfate, 17 SUDAFED, 21 sulfacetamide 10%, 24 sulfacetamide prednisolone phosphate 10% 0.25%, 24 sulfamethoxazole trimethoprim, 6 sulfasalazine, 17 sulfasalazine delayed-rel, 17 sulindac, 3 sumatriptan, 12 SUMYCIN, 5 SUSTIVA, 5 SYNTHROID, 16 tacrine, 11 tacrolimus, 19, 23 TAGAMET, 16 TAMBOCOR, 9 TAMIFLU, 6 tamoxifen, 7 TAPAZOLE, 15 TARGRETIN, 7 tazarotene, 23 TAZORAC, 23 TEGRETOL, 10 TEGRETOL-XR, 10 temazepam, 11 TEMODAR, 7 TEMOVATE, 23 temozolomide, 7 TENEX, 8 TENORMIN, 9 terazosin, 8 terbinafine, 5 terbutaline, 21 TESSALON, 20 tetracycline, 5 THEOCHRON, 22 theophylline ext-rel caps 12 hr ; , 22 theophylline ext-rel tabs, 22 theophylline liquid, 22 thiamine, 20 THICK-IT, 19 thioguanine, 7 thyroid, 16 tiagabine, 11 TIAZAC, 10 TIGAN, 16 timolol hemihydrate, 25 timolol maleate, 25 TIMOPTIC, 25 37.
GENERIC BRAND ANTI-INFLAMMATORY AGENTS generic Decadron Fluorometholone generic, FML Forte Forte S.O.P. Prednisolone Acetate generic Econopred Plus Mild Prednisolone Phosphate generic Inflamase Mild BETA-BLOCKERS generic Betoptic S Levobunolol generics only Timolol generics only Timolol Timoptic Ocudose VASOCONSTRICTORS generics only MISCELLANEOUS OPHTHALMIC AGENTS --Cyclosporine Restasis OSTEOPOROSIS AGENTS Alendronate Calcitonin Risedronate Teriparatide OTICS Antipyrine Benzocaine generic AB Otic Glycerin Triethanolamine Cerumenex ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMBINATIONS Acid HC generics only Ofloxacin Floxin Otic Polymyxin-B Neomycin HC generic Cortisporin RESPIRATORY ASTHMA ANTI-ASTHMATIC AGENTS . Montelukast Singulair Zafirlukast Accolate Corticosteroids . Beclomethasone Qvar Budesonide Inhaler Soln Pulmicort Fluticasone Inhaler Rotadisk Flovent Triamcinolone Acetonide Azmacort Sympathomimetics . Albuterol generics only Albuterol Inhaler, CFC-free Proventil HFA Ventolin HFA Albuterol SR Tablets Proventil Repetabs Volmax Formoterol Foradil Metaproterenol generic Alupent Metaprel Salmeterol Serevent Terbutalije generic Brethine Xanthine Derivatives . Aminophylline Aminophylline Theophylline IR SR gen Uniphyl Theo-24 Theophylline SR Sprinkle Theo-Dur Sprinkles OTHER RESPIRATORY ASTHMA AGENTS --Albuterol Ipratropium Combivent Cromolyn Sodium generics only Cromolyn Sodium Intal Inhaler Dornase Alfa Pulmozyme Ipratropium Bromide generics only Ipratropium Bromide Atrovent Inhaler Omalizumab Xolair Pentamidine Nebupent Potassium Iodide generic SSKI Salmeterol Fluticasone Advair Diskus Fosamax Miacalcin NS Actonel Forteo and lioresal.
Extended this to demonstrate the presence of 8-adrenoceptors in articular blood vessels. The , i-adrenoceptor agonist isoprenaline potently dilated blood vessels in the posterior capsule of the knee joint, despite its transient lowering effect on systemic blood pressure Fig. 2 ; , which tends to counteract the former effect. These results along with the fact that the dilator responses to adrenaline, isoprenaline and nerve stimulation were virtually abolished by propranolol suggests that , J-adrenoceptors are present in this vascular bed. A previous study from this laboratory using an isolated rabbit knee joint preparation Ferrell & Khoshbaten, 1989 ; failed to demonstrate the presence of f, -adrenoceptors, but such in vitro results have to be interpreted with caution. In a recent in vivo study of the subtypes of a-adrenoceptors in articular blood vessels Najafipour & Ferrell, 1993 ; a2-adrenoceptors predominated, whereas the previous in vitro investigation showed a predominance of aXadrenoceptors Ferrell & Khoshbaten, 1989 ; . Such differences could arise due to the different methodologies used in these studies. Ferrell & Khoshbaten 1989 ; measured changes in perfusion pressure as an indirect indicator of resistance, whereas laser Doppler flowmetry was used in this in vivo study. The former technique is likely to reflect changes in the calibre of the larger resistance vessels, whereas laser Doppler flowmetry reflects changes in the smallest arterioles and in the capillaries. In addition, there may be differences in the responsiveness of blood vessels resulting from changes in vessel tone or the absence of circulating vasoactive substances in vitro. To investigate the nature of these , 8-adrenoceptors, more specific agonists and antagonists were employed. Although the dilator responses to dobutamine, a selective , -agonist Weiner, 1980a ; , were smaller than the responses to isoprenaline Fig. 4A ; , the potent inhibitor effect of the selective , 3-antagonist atenolol Robertson, Kaplan, Caldwel & Speight, 1983 ; on the dilator responses to both of these agents Fig. 4B ; suggests that these effects are mediated via 31-adrenoceptors. The cross-reaction of atenolol with i2adrenoceptors is unlikely because the transient changes in blood pressure due to isoprenaline or salbutamol injection are not significantly different before and after atenolol Fig. SB ; , suggesting that 82-adrenoceptors in other vascular beds are unaffected by atenolol. The difference in potency on blood flow of isoprenaline and dobutamine may reflect differences in their affinities for fl1-adrenoceptors or the additive 2 effect of isoprenaline. The specificity for fi1-adrenoceptors of dobutamine and atenolol is evident from the negligible hypotensive effect of dobutamine, and inability of atenolol to block the depressor effects of isoprenaline and salbutamol Figs 4B and SB ; , which are exerted via systemic ?2-adrenoceptors in other vascular beds, particularly in skeletal muscle. On the other hand, isoprenaline and salbutamol seemed to be equipotent based on their hypotensive effects Fig. SB ; , but the former showed a more powerful vasodilating effect on joint blood vessels Fig. 5 A ; . This may reflect an additive effect on , ll-adrenoceptors. Dobutamine is used in the treatment of cardiac failure mostly for its positive inotropic effect on the human heart. In the present study and at the dose used, it showed no chronotropic effect on the rabbit heart Figs 4A and 6A ; , although isoprenaline showed clear chronotropic effects. This could be due to dobutamine having less chronotropic effects Tuttle & Mills, 1975 ; , or may reflect species differences in , 8-adrenoceptor subtypes in the heart. The 82-agonists salbutamol and terbutaline appeared to be much less potent in joint blood vessels than isoprenaline and dobutamine Figs 4A and SA ; . Although their dilator effects were somewhat decreased by atenolol, they did not differ significantly from control values Fig. SA ; . The , 82-antagonist ICI118551 failed to inhibit the dilator responses to isoprenaline and dobutamine Figs 6B and 7A ; , although the smaller dilator responses to.
Figure 4 Change in [35S]GTPgS binding to rat uterine membrane from days 15, 18, 20 and 22 of pregnancy by various concentrations of terbutaline. Points are means S.E.M. from 3 separate experiments carried out in triplicate. The basal value is that of [35S]GTPgS binding without terbutaline stimulation and was regarded as 0 and bethanechol. What is TerbutalineIncomplete communication and documentation Selected Case Reports Case #1: An IV pump was originally programmed to deliver 2 mL minute of a pitocin infusion but was inadvertently changed to deliver 20 mL minute. This resulted in the patient receiving a 10-fold overdose for several minutes before the error was discovered. The patient developed tetanic contractions lasting 6 minutes. The pitocin IV was stopped, the patient's obstetrician was called and the patient was given a bolus of fluid, terbutaline, and oxygen. The baby's fetal heart rate experienced 5 minutes of deceleration in the 50 - 80 beats per minute range, but returned to baseline in the120's. The uterine tone also returned to normal. Case #2: An epidural infusion consisting of bupivacaine 0.1% with epinephrine and 0.8 mcg mL fentanyl was ordered to infuse at 15mL hour. The patient was also receiving lactated ringers solution as the maintenance IV to be infused at 125mL hour. A nurse discovered however, that the epidural IV line in channel A of the IV pump ; was infusing at 125mL hour while the lactated ringers was labeled as an epidural in channel B infusing at 15mL hr. The patient inadvertently received the excessive dose of bupivacaine epinephrine fentanyl over approximately 2 hours. The infusions were stopped, ephedrine and fluids were given bolus, vitals monitored every 5 minutes and the epidural was resumed when the patient was ready for delivery. There were no adverse outcomes for the mother or baby. Case #3: In preparing for a scheduled caesarian section, the anesthesia provider prepared a pitocin infusion 20 units in 1000 mL ; that was intended to be given following delivery of the placenta. The IV tubing was primed with the pitocin solution, however, the anesthesia provider failed to close the roller clamp. About 300 mL of the pitocin solution rapidly infused prior to the induction of anesthesia or the surgical incision. The patient experienced titanic uterine contractions and the baby's heart rate decreased to 60-70 beats per minute. An emergency caesarian section had to be performed. The mother and baby recovered without permanent harm. Case #4: Upon admission, a patient stated she was allergic to sulfa and cefaclor. A physician in labor and delivery ordered cefotetan 1 gram IV now. After the drug was administered, the patient developed a flushed face, welts, and complained of itching on the face, back, and chest. Case #5: A physician ordered insulin 10 units in 100mL of normal saline to be infused at 1 unit hour 10mL hour or 0.1unit mL ; . The pharmacy prepared the IV bag as ordered, however, the administering nurse thought the standard insulin concentration was 1unit mL and therefore programmed the pump to infuse the insulin bag at 1 mL hour 0.1unit hour ; resulting in a 10 fold under dosing. Several hours later, the patient's blood glucose levels were elevated prompting the physician to order an increase in the insulin infusion rate to 11 mL hour. The error was discovered when nursing requested an additional IV bag from the pharmacy. FIG. 3. Combined effects of terbutaline, TPA, and OAG on phosphatidylcholine secretion. The alveolar type I1 cells, which and bicalutamide. Terbutaline baby effects
In one study 4 ; of patients with brittle asthma defined by wide diurnal variations in pef rates ; , twice-daily subcutaneous administration of terbutaline improved symptoms, medication use, and pef rates and casodex and terbutaline.
T TAGAMET .35 TALACEN .15 TALADINE.35 TALWIN NX.16 TAMBOCOR.19 TAMIFLU .5 tamoxifen citrate.10 tana pse.46 tana r-12 .46 tanacof-a 12 .46 TANAFED.47 TANAFED DP.47 tanatan rf .46 tanavan.46 TAPAZOLE .31 TARABINE PFS.11 TARCEVA.11 TARGRETIN.11 TAVIST.44 TAXOL .12 TAXOTERE .12 TAZICEF.6 TAZORAC.25 taztia XT .20 tbc .27 TE ANATOXAL BERNA .36 tebamide.33 TEGRETOL.12 TEGRETOL XR .12 TEMOVATE .27 TEMOVATE EMOLLIENT .27 TENEX .19 TENORETIC 100.21 TENORETIC 50 .21 TENORMIN .20 TENORMIN I.V 20 terak.40 TERAZOL.38 TERAZOL 7 .38 terazosin .48 terazosin HCl .19 terbutaline sulfate.47 terconazole.38 TERRAMYCIN IM.9 TERRAMYCIN W POLYMYXIN .40 tesamone-100.32 TESLAC .12 TESTIM .32 testomar .28 testosterone.32 testosterone cypionate .32 testosterone enanthate .32 testosterone propionate .32 75.
The allele distribution of the AHSG polymorphism Thr230Met was in Hardy-Weinberg equilibrium, and the frequency of the minor allele T Met ; was 40%. In Table 1, the effect of Thr230Met on clinical parameters is shown. No effect of the genotype on any of the examined clinical parameters was found. The results of the subcutaneous fat cell lipolysis measurements are shown in Table 2. There were no differences between the genotypes, either in basal lipolysis, in maximum stimulation of lipolysis induced by dobutamine, terbutaline, or forskolin or in maximum inhibition of lipolysis induced by clonidine. In contrast, with respect to lipolytic adrenoceptor sensitivity, a marked effect was found for terbutaline. Men homozygous for the AHSG rs4917 Met allele had approximately 1.5 log units higher sensitivity for adipocyte 2-adrenoceptor stimulation than men heterozygous or homozygous for the Thr allele P 0.0008 comparing three genotypes, P 0.0024 after Bonferroni adjustment for multiple comparison of adrenoceptor subtype sensitivity ; . In other words, 2-adrenoceptor sensitivity of fat cells from Met-allele-homozygous men was about 35-fold higher than that of fat cells from men with Thr Met or Thr Thr genotype Fig. 1 ; . The genotype effect on terbutaline sensitivity remained statistically and bisoprolol.
Placebo in trials to assess the efficacy of new antidepressant medications.11 It has been argued that the use of placebo assignment in such trials remains justified because the demonstraAuthor Affiliations and Financial Disclosures are listed at the end of this article. Corresponding Author and Reprints: B. Timothy Walsh, MD, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Dr, Unit 98, New York, NY 10032.
SYMAX-SR SYMBYAX SYMLIN SYMMETREL SYNAGIS SYNALAR SYNALGOS-DC SYNAREL SYNERA SYNERCID SYNTHROID SYPRINE syringe w-ndl, disp., insulin T-4 GEL TABLOID TACLONEX TAGAMET TALACEN TALADINE TALWIN TALWIN NX TAMBOCOR TAMIFLU CAPSULES TAMIFLU SUSPENSION tamoxifen citrate TANA PSE TANA R-12 TANACOF-XR TANAFED DP TANATAN RF TANAVAN TANNATE PEDIATRIC TAPAZOLE TARCEVA TARGRETIN CAPSULES TARGRETIN GEL TARKA TASMAR 119 47 55 TAXOTERE TAZICEF TAZORAC TAZTIA XT TE ANATOXAL BERNA TEGRETOL TEGRETOL-XR TEMOVATE TEMOVATE E TENEX TENORETIC 100 TENORMIN TERAZOL 3 TERAZOL 7 terazosin hcl terbutaline sulfate terconazole TERNAMAR TESLAC TESTIM TESTOPEL testosterone testosterone cypionate testosterone enanthate testosterone propionate TESTRED tetanus toxoid TETANUS TOXOID ADSORBED TETANUS DIPHTHERIA TOXOID tetracycline hydrochloride TETRA-MAG TEVETEN 400MG TEVETEN 600MG TEVETEN HCT TEV-TROPIN TEXACORT THALITONE THALOMID 37 33 64 THEO-24 THEOCAP THEOCHRON THEOMAR GG theophylline theophylline cr theophylline er theophylline sr theophylline td THERACYS THERA-FLUR-N THERMAZENE THIOLA thioridazine hydrochloride thiotepa thiothixene THYMOGLOBULIN thyroid THYROLAR-1 TIAZAC 120MG TIAZAC 180MG TIAZAC 240, 300, 360, TICE BCG TICLID ticlopidine hydrochloride TIGAN TIKOSYN TILADE TIME-HIST TIMENTIN TIMOLIDE timolol maleate timolol maleate ophthalmic TIMOPTIC TIMOPTIC OCUDOSE TIMOPTIC-XE TINDAMAX TIS-U-SOL 24 tizanidine hydrochloride T-NAF TOBI TOBRADEX tobramycin sulfate tobramycin sulfate and sodium chloride TOBRASOL TOBREX TOFRANIL TOFRANIL-PM tolazamide tolbutamide TOLECTIN DS TOLINASE tolmetin sodium TOPAMAX TOPICORT TOPICORT LP TOPOSAR TOPROL XL TORADOL ORAL torsemide TOURO ALLERGY TOURO LA TOURO LA-LD T-PERIO TPN ELECTROLYTES FTV TRAC TRACLEER tramadol hcl tramadol hcl and acetaminophen TRANDATE TRANDATE IV TRANSDERM-SCOP tranylcypromine sulfate TRAVASOL TRAVATAN TRAVATAN Z.
Cairns & dulhunty 1993b ; showed that terbutaline's force potentiating effects on rat soleus muscle fibres were not due to changes in the action potential, na + k + pump activity, extracellular ca 2 + influx, or glycolysis, and speculated that the drug acted through a cyclic amp-dependent increase in sr ca release.
Table 23.1. Additional Dicarboxylate-containing Angiotensin Converting Enzyme Inhibitors, because terbutaline pharmacology. Terbutaline iv pushTerbutaline effects on metabolismAdc stethoscope 603, genome mapping genetics, hyperexplexia or stiff baby syndrome, neutral posture 5500 chair and duricef 500mg capsules. Flumadine versus tamiflu, erythrocyte sedimentation rate method, occiput listings and thoracic outlet syndrome exercises and stretches or how fast does kidney cancer grow. Autism firm law terbutalineTerbutaline baby, terbutaline risks, what is terbutaline, terbutaline baby effects and terbutaline iv push. Tedbutaline effects on metabolism, autism firm law terbutaline, terbutaline pump side effects and use of terbutaline or terbutaline sulphate sr. Copyright © 2009 by Allcheap.tripod.com Inc.
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