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Of the oral mucosa may be sufficient to arrive at an initial diagnosis of BMS, in the absence of overlapping overwhelming conditions Fig. 2, part I ; . Details about quality, intensity, onset, occurrence, persistence, overall duration, evolution, and site s ; of pain symptoms are essential for the adequate assessment of pain. Symptomatically, BMS must be differentiated from other chronic pain conditions such as painful traumatic inflammatory immuno-mediated stomatitis or orofacial pain disorders Table 2 ; . The location of the main symptom pain ; in the oral mucosa excludes diseases such as atypical facial pain, atypical odontalgia, and idiopathic facial arthromyalgia, which affect bones, teeth, muscles, and articulation, respectively. Specific details about pain, such as its localization, overall duration, and daily evolution, lead to a suspicion of BMS symptoms, rather than persistent oral mucosal lesions. In the latter group, in fact, pain is commonly unilateral, with some exceptions, such as diffuse oral infections and erosive lichen planus. However, in all these conditions, symptoms are characterized by periods of remission and increased discomfort during eating. The suspicion of BMS symptoms can be reinforced by detection of the other symptoms commonly associated with BMS, such as dry mouth, taste changes, and sensory anomalies. Further aid may come from the identification of possible extensive abuse of xerostomia-inducing drugs. Patients who fulfill the inclusion symptomatic criteria for BMS Fig. 2, part Ia ; should be additionally evaluated for the potential psychogenic component of their pain, with the use of psychometric instruments Carlson et al., 2000 ; , such as the McGill Pain Questionnaire MPQ ; Melzack, 1987 ; and or the Multidimensional Pain Inventory MPI ; Kerns et al., 1985 ; . An objective assessment of the pain should also be performed. Both pain intensity and evolution can be recorded and monitored via VAS. Examination of the oral mucosa in these patients is crucial Fig. 2, part Ib ; . BMS, in fact, must be differentiated from oral mucosal lesions Bergdahl and Anneroth, 1993; Ship et al., 1995 ; that are accompanied by oral burning or pain-like symptoms, such as traumatic lesions, specific infections e.g. candidiasis ; , and chronic erosive ulcerative stomatitis aphthous stomatitis, erosive lichen planus, pemphigoid, pemphigus, etc. ; . Neoplastic lesions must be excluded as well. The lack of oral mucosal pathology should lead one toward the diagnosis of BMS Fig. 2, part Ic ; . Disorders that can potentially arise from local conditions.
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GENERAL Introduction BASF is a return-focused global company generating long-term growth and protability from its chemical businesses, positioning itself for continuing growth in health and nutrition and strengthening its presence in European and other oil and gas markets. The company oers a wide range of products, including high-value chemicals, plastics, colorants, automotive and industrial coatings, crop protection products, pharmaceuticals, ne chemicals, petrochemicals, crude oil and natural gas. BASF is comprised of the parent company, BASF Aktiengesellschaft of Ludwigshafen, Germany, and 149 consolidated subsidiaries. The company has customers in more than 170 countries and operates production sites in 38 countries. For the year ended December 31, 1999, BASF reported sales of 429.47 billion, income from operations of 42.01 billion and net income after taxes and minority interests of 41.24 billion. Europe accounted for 58% of BASF's total sales in 1999. BASF's activities in North America comprised of the United States, Mexico and Canada ; , accounted for 23% of sales. The Asia, Pacic Area, Africa region contributed 13% to sales, while South America accounted for 6%. Although Europe remains the company's primary market, BASF expects that its activities outside of Europe will make an increasingly larger contribution to its business. BASF plans to invest approximately 42.5 billion between 2000 and 2004 in its activities in North America, where it currently produces approximately 90% of the products it sells there. BASF has also set a goal of generating 20% of its worldwide sales in the Asia-Pacic region by 2010, with 70% of these sales originating from local production. BASF is committed to strengthening its nancial performance and competitive position by bolstering cyclically resilient operations, achieving cost and market leadership in operations that are sensitive to economic pressures and expanding its activities in growth regions such as Asia as well as North and South America. One of BASF's nancial objectives is to achieve an average annual increase of at least 10% in income from operations on a comparable basis between 2000 and 2002. BASF's long-term strategy and activities are guided by the principles of Sustainable Development. The company's objective is to meet the economic, ecological and social needs of today's society without compromising the ability of future generations to meet their own needs. BASF contributes to Sustainable Development by participating in the worldwide ""Responsible Care'' initiative developed by companies in the global chemical industry. BASF's aims are to avoid accidents, to prevent its activities from impairing human and animal health and to tailor its product range to the tenets of sustainability. Business Segments BASF has ve separate business segments: Chemicals, Plastics & Fibers, Colorants & Finishing Products, Health & Nutrition and Oil & Gas. These business segments encompass BASF's 15 operating divisions. For nancial reporting purposes, BASF treats the three operating divisions of BASF's Health & Nutrition business segment as three separate reportable operating segments: Pharmaceuticals, Fine Chemicals and Crop Protection. Chemicals BASF produces a full range of chemicals in a highly integrated approach to manufacturing. BASF's chemical production starts with basic petrochemicals and inorganic chemicals substantially for captive use within the company and extends to high-value chemicals and related products sold to 1 and bethanechol.
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Santos, Margarida; Barros, Luisa Lisbon University The most recent approaches conceptualize occupational stress as the result of a transaction between professional demands and a worker's cognitions and coping abilities. The constructivist-developmentalist perspective defends that these individual cognitions significations ; can be structured in levels that, similar to Piaget conceptualization, are progressively more complex, flexible and integrative. Stress and coping strategies are then perceived differently in each level of development. OBJECTIVE: The central objectives of this study are: 1 ; to identify levels of perceived stress and self-efficacy; and, 2 ; to analyse, under the constructivistdevelopmentalist perspective, the significations of 150 Portuguese Health Professionals 54 Pharmacists; 55 Physiotherapists; 41 Radiotherapists ; , about three potential stressful situations dilemmas ; at work, namely: an interpersonal conflict; overload; and dealing with a terminally ill patient. METHOD: The participants 1 ; were asked to answer a demographic questionnaire that included two subjective scales on stress and self-efficacy and 2 ; were given the three dilemmas and asked to write about their perceptions of those situations, and their ways of dealing with them. The significations were then analysed by means of a developmental sequence Joyce-Moniz, 1993 ; already used in several similar studies Barros, 1992; Grilo, 1999; Nordeste, 1997; Santos, 1997 ; . RESULTS: The results showed that different occupational groups used different levels of significations in the three dilemmas. These differences may be due to occupational characteristics and cultural as well as professional education issues, and can be responsible for different ways of perceiving and reacting to stressful situations at work.
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Surprisingly, C. chinensis attenuated the scopolamine-induced amnesia in rats when given orally for 1 week 122 ; . What is the role of dopamine on memory? The dopamine D3 receptor has been extensively studied in animal models of drug abuse and psychosis; however, less is known of its possible role in cognitive functions. Laszy et al. investigated the effects of different D3 antagonists and a partial agonist on spatial learning performance in a water labyrinth test, and clearly demonstrated that D3 antagonists, such as SB-277011 24 mg kg orally ; attenuated the memory impairments caused by FG-7142, suggesting that dopamine D3 receptor antagonists have potentials in improving cognition associated with several psychiatric disorders 123 ; . Cimicifuga foetida L., or sheng ma Chinese ; , is an herb that grows from a rhizome to a height of 2 m China, Bhutan, India, Kazakhstan, Mongolia, Burma, and Siberia. The leaves are pinnate; the petiole grows up to 15 long; and the leaf blade is lobed and serrate. The flowers are 4 mm in diameter and the petals are broadly elliptic. The fruits are 814-cm 2.55-mm follicles Fig. 79 ; . The drug consists of the rhizome, which is used to treat headhaches, sore throat, dysentery, measles, smallpox, ulcers, antidotal, and calming in China. The pharmacological potential of this plant is, to date, unveiled. Note that the plant elaborates a series of triterpenoid saponins and original cycloartane triterpenes, such as neocimicidine of the cycloartane 124, 125 and zebeta and lioresal, for example, lioresal injection.
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