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A police officer shall be considered "on duty" while on any assignment approved by the chief of the police department of the municipality he or she serves, whether the assignment is within or outside the municipality. b ; If a police officer on disability pension dies while still disabled, the disability pension shall continue to be paid to his or her survivors in the sequence provided in Section 3-112. c ; From and after July 1, 1987, any pension payable under this Section shall be at least $400 per month, without regard to the fact that the disability or death of the police officer occurred prior to that date. If the minimum pension established in Section 3-113.1 is greater than the minimum provided in this Section, the Section 3-113.1 minimum controls. d ; A disabled police officer who 1 ; is receiving a pension under this Section on the effective date of this amendatory Act of the 91st General Assembly, 2 ; files with the Fund, within 30 days after that effective date and annually thereafter while the pension remains payable, a written application for the benefits of this subsection, including an affidavit stating that the applicant has not earned any income from gainful employment during the most recently concluded tax year and a copy of his or her most recent Illinois income tax return, 3 ; has service credit in the Fund for at least 7 years of active duty, and 4 ; has been receiving the pension under this Section for a period which, when added to the officer's total service credit in the Fund, equals at least 20 years, shall be eligible to receive an annual noncompounded increase in his or her pension under this Section, equal to 3% of the original pension. The Fund may take appropriate steps to verify the applicant's disability and earnings status, and for this purpose may request from the Department of Revenue a certified copy of the applicant's Illinois income tax return for any year for which a benefit under this Section is payable or has been paid. The annual increase shall accrue on each anniversary of the initial pension payment date, for so long as the pension remains payable to the disabled police officer and the required annual application is made, except that the annual increases under this subsection shall cease if the disabled police officer earns income from gainful employment. Within 60 days after accepting an initial application under this subsection, the Fund shall pay to the disabled police officer, in a lump sum without interest, the amounts resulting from the annual increases that have accrued retroactively. This subsection is not limited to persons in active service on or after its effective date, but it applies only to a pension that is payable under this Section to a disabled police officer rather than a survivor ; . Upon the death of the disabled police officer, the annuity payable under this Section to his or her survivors shall include any annual increases previously received, but no additional increases shall accrue under this subsection. Source: P.A. 91-939, eff. 2-1-01.

This statement is not part of the Regulations. ; Summary This Regulatory Impact Analysis Statement RIAS ; deals with the inclusion into the Packaging and Transport of Nuclear Substances Regulations PTNSR ; of the latest version of the International Atomic Energy Agency's IAEA ; Regulations for the Safe Transport of Radioactive Material, 1996 Edition Revised ; , No. TS-R-1 and with two consequential amendments to the General Nuclear Safety and Control Regulations GNSCR ; . The changes are designed to complement existing regulatory practices. For the most part, the amendments update existing references made to the IAEA Regulations throughout the PTNSR and introduce a number of new requirements, such as Type C packages for air transport of large quantities of nuclear substances and the certification of a new type of nuclear materials called Low Dispersible Radioactive Materials LDRM ; as discussed later in this RIAS. Background As Canada's nuclear regulatory agency, the Canadian Nuclear Safety Commission CNSC ; regulates all activities related to the use of nuclear energy and nuclear substances in Canada including the packaging and transport of nuclear substances. The regulation of the packaging and transport of nuclear substances is a jointly shared responsibility with Transport Canada. The CNSC regulations primarily are concerned with health, safety, security and protection of the environment related to the special characteristics of nuclear substances. These Regulations are complemented by those issued by Transport Canada which have general application to the transport of all classes of dangerous goods. All industrialized countries use the recommendations of the IAEA to regulate the packaging and transport of radioactive materials. Canada is no exception. Canada applied the requirements of the IAEA Regulations for the Safe Transport of Radioactive Material as the basis for regulating the transport of radioactive nuclear substances since their initial adoption in the international community. The PTNSR were enacted in May 2000, SOR 2000-208, as one of nine Regulations made under the Nuclear Safety and Control Act NSC Act ; and are based on the 1985 edition as amended 1990 ; of the IAEA Regulations for the Safe Transport of Radioactive Material. The IAEA is committed to periodically updating and revising their regulations to ensure that they remain relevant, useful and suitable for worldwide use. In keeping with this commitment, the IAEA issued a 1996 edition of the Regulations for the Safe Transport of Radioactive Material, known as TS-R-1, that was implemented in 2001. The purpose of this amendment to the PTNSR is to update the regulatory requirements to the 1996 edition of the IAEA Regulations. The CNSC, including its predecessor the Atomic Energy Control Board AECB ; , has been a major participant in the development of the IAEA Regulations. In formulating a Canadian position on radioactive materials transportation issues, the CNSC has communicated regularly with Transport Canada and major stakeholders. Transport Canada is normally represented at transport, because indocin manufacturer.
Indomethacin Indkcin ; has been the most reported NSAID to blunt antihypertensive effects. However, given the mechanism of the interaction, most, if not all, NSAIDs are likely to interact. There is some controversy with this issue related to sulindac Clinoril ; .37, 38 With the introduction of cyclooxygenase type 2 inhibitors for the treatment of pain and inflammation, one wonders if the same interaction is possible. To date, there has been one published case report of a 59-year-old man who was successfully treated with lisinopril, 10 mg day. 39 After staring rofecoxib Vioxx ; , 25 mg day, blood pressure control was diminished. Eventually, the patient maintained good blood pressure control with lisinopril, 20 mg day, and rofecoxib, 25 mg day. Although the mechanism for the interaction has not been established, it is theorized that rofecoxib-induced inhibition of renal prostaglandins is probable.39 Lithium is considered a narrowtherapeutic-index drug. Thiazide diuretics, ACE inhibitors, and ARBs can increase lithium concentrations by interfering with lithium's renal excretion.1, 2 In general, thiazides should be avoided in patients prescribed lithium. If a diuretic is needed, a loop diuretic such as furosemide is recommended. Patients who are on ACE inhibitors or ARBs and lithium should have lithium levels checked and should be counseled to seek medical attention for signs of lithium toxicity. These include nausea, vomiting, diarrhea, coarse tremor, slurred speech, and disorientation. 1 In April 1997, Eisai America Inc. and Eisai Pharmatechnology, Inc. merged with Eisai Inc. * 2 In April 1997, Eisai Europe Ltd. merged with Eisai Ltd. * 3 In July 1997, Eisai-Sandoz GmbH & Co. KG was renamed Eisai-Novartis GmbH & Co. KG, for example, indocin sr 75.
Polyketides are a rich source of therapeutic agents used in human medicine, including antibiotics, antifungals, immunosuppressants and anticancer agents. Sometimes the natural producer of these polyketides can be difficult, or impossible, to cultivate. More often, the titre of the desired polyketide is very low. Rather than focus on development of many individual polyketide-producing organisms, scientists at Kosan Biosciences have developed three Streptomyces spp. as generic hosts for expression of polyketide synthase PKS ; genes that have been cloned from the original producers. The three hosts are, Streptomyces coelicolor, S. fradiae and Saccharopolyspora erythraea. These three streptomycetes underwent conventional strain improvement and fermentation development to enhance the production of their endogenous polyketides; then the endogenous PKS. Amprenavir, and the newly approved pro-drug formulation, fos-amprenavir, have been studied in both treatment nave and treatment experienced patients. Fos-amprenavir has substantial exibility, and can be used as a sole PI, twice daily, or boosted with ritonavir and given either once or twice daily. When used in treatment experienced patients, fos-amprenavir should be dosed twice daily with ritonavir. In clinical studies, fos-amprenavir was found to be quite effective among patients with low CD4 count and or high viral load. Fos-amprenavir has a favorable metabolic prole compared to several other PIs, but not to the same extent as atazanavir. Amprenavir has been used successfully when combined with Kaletra, despite a drug interaction. However the combination of fos-amprenavir and Kaletra has a signicantly more profound interaction, making the use of this combination contraindicated. --Stephen L. Becker, MD and isordil.

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Lar hydrogen bonds in the unit cell of the title complex: one is the O--H O intermolecular hydrogen bonding between the oxygen atoms of coordinated water molecules and the oxygen atoms of the crystal water molecules, the angle of which is 158 7 ; O 4 ; --H 4A ; O 7 ; #4 the other is the O--H O intermolecular hydrogen bonding between the oxygen atoms of the coordinated water molecules and the oxygen atoms of chelated Sal anions, with bond angle of 151 7 ; O 4 ; --H 4B ; O 3 ; #2 the last is the O--H O intermolecular hydrogen bonding between the oxygen atoms of the coordinated water molecules and the oxygen atoms of bridged Sal anions, the bond angle of which is 98 6 ; addition, there exists one type of O--H O intramolecular hydrogen bonds between the oxygen atoms of the coordinated water molecules and the oxygen atoms of bridged Sal anions, the bond angle of which is 88 6 ; --H 4A ; O 1 . All these hydrogen bondings link up the complex units, resulting in a 3-D network and making the whole network structure system stable. The detailed data of hydrogen bonding are shown in Table 3. The ultraviolet absorption spectrum of [Dy Sal ; 3 H2 O ; 2H2 O]n 10-4 mol dm-3 ethanol solution ; Fig. 5 ; shows a domain absorption band at 270 nm, which is attributed to the characteristic absorption of Sal. This indicates that Sal is the energy donor for the luminescence of Dy3 + ion. The excitation spectrum exhibits that the effective energy absorption mainly takes place in the narrow 253, for example, indocin 50.
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