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P erfusion to unventilated lung ; greater than 6 percent of the cardiac output. Apart from the small shunts, no subject showed perfusion to lung regions with less than 0.1. The mean log moderately from the ideal SD of 0.98 severe curves in patients ViJQ curves in the 7-10 deviated middle Table markrange 2 ; The. Prepared by Katie Smith, Medicines Review & Primary Care Support Pharmacist, East Anglia Medicines Information Service, Ipswich Hospital. For further information please contact Katie on 01473 704435 or katie.smith ipswichhospital.nhs, for example, xanax. A result, our mapping from physiological state space to conscious states is an approximation that further experimentation can only serve to refine. IV. CONCLUSIONS In view of our goal, stated in the Introduction, to begin to bridge interdisciplinary gaps in the study of sleep and dreaming, we have reviewed contemporary perspectives primarily from research psychology, neuropsychology, neurobiology and clinical sleep medicine. Our AIM state-space model and a revised Activation-Synthesis theory of dreaming, summarized below, constitute our current and necessarily approximate synthesis of these data which we hope will stimulate many future hypothesis-testing experiments. With regard to the areas not covered here, we refer the reader to published works and we eagerly await future reviews ; on dreaming and consciousness from scientists and scholars with specific expertise in clinical psychology, philosophy, literature, neural networks, artifical intelligence, as well as functional-evolutionary and molecular biology perspectives on sleep and dreaming. We have shown that phenomenological differences between waking, NREM and REM sleep are measurable. In our view, these differences are so great that they represent qualitative differences. A better understanding of the physiological processes underlying dream construction may be necessary before this issue can finally be laid to rest. But even when dream features appear to be specifically linked to distinctive REM physiology, interpretations can still be cast toward either camp. Hong et al. 1997 ; reported an impressive correlation between visual imagery and REM density r 0.8 ; , which we would argue as evidence for a dependence of dream imagery on a qualitative feature of REM sleep. In contrast, Antrobus et al. 1995 ; consider this to be another example of the simple dependence of dream content on levels of brain activation, arguing that rapid eye movements are not under strict brainstem cholinergic control, but come increasingly under the control of the frontal eye fields as general cortical activation increases.

This study was supported in part by National Institutes of Health grants 1RO1 HL67232, 1PO1 HL56693, and RR00095. Dr Jordan is supported by the Deutsche Forschungsgemeinschaft and receives a Helmholtz scholarship from the Max-Delbrueck-Centrum MDC ; . The authors would like to thank the nurses and personnel of Vanderbilt's General Clinical Research Center for their invaluable help in the evaluation of these patients and serevent. Kurt cobain, the grunge rock singer, collapsed and slipped into a brief coma a month before his suicide last year after ingesting rohypnol with champagne in a hotel room in rome.

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