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Vera Rogiers. Department of Toxicology, Vrije Universiteit Brussel, Brussels, Belgium The safety assessment of cosmetics in the EU is based on three important articles, present in Council Directive 76 768 EEC amended by the 6th Amendment, and on the 7th Amendment. Article 2 requires safety for human health and places the full responsibility on the manufacturer, the first importer in the EU or marketer. Article 7 underlines that the safety of cosmetics is based on the safety of the ingredients, namely their chemical structure, toxicological profile and exposure. Article 4 states that safety for human health must be guaranteed without animal tests carried out on EU territory.- The 7th Amendment allows 6 years for obtaining validated alternatives to replace all safety tests with the exception of repeated exposure tests, for which 10 years are provided. In the safety evaluation of cosmetic ingredients two distinct channels are operative: i ; the safety evaluation of colouring agents, preservatives and UV-filters, taken up in Annexes IV, VI and VII of the Directive, respectively, and of ingredients restricted in concentration and application Annex III ; is done by the SCCNFP Scientific Committee on Cosmetics and Non-Food Products ; on the basis of raw material dossiers provided by the industry; ii ; for all other ingredients, the safety evaluation is done by a safety assessor in the context of a cosmetic product dossier. Indeed, the 6th Amendment requires a technical information file for all finished cosmetic products coming on the EU market. It must cover both safety and efficacy, for instance, micardis sales. BENGT BJORKSTIgN' AND PAUL G. QUIE * Department of Pediatrics, University of Minnesota School of Medicine, Minneapolis, Minnesota 55455. I very sad to say that this will be my last column as Medical Students Officer for the University of London. The last two years has seen huge changes in medstudent issues within London and I proud to look back and think what the other officers and I have achieved. Perhaps the most telling sign of the leaps and bounds that the five schools and ULU have made for medical students has been this paper. When I started it up back in February last year, my main aim was to get information out to all of you about the changes on the horizon with foundation programmes. Even with that first edition, which we managed to turn around in a week and a half, I received an unprecedented level of support from students and staff alike. There have been a large number of students involved with this fabulous publication since, but I in awe of the excellent job that Rohin and his team have done this year in creating a paper and website that is engaging and popular beyond anything I had hoped for. Our five schools have worked closer than ever, in a united purpose, to promote the interests of London medics to the, for example, micardis hcl.

Valley Baptist Health Plan, Inc., a Health Plan with a Medicare Contract.

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Speaking and weakness in the right extremities. During the acute period post-stroke period, he received conventional medication and speech therapy. He was then discharged for out-patient treatment. Five months after the stroke, the patient's speech consisted only of simple words, that is, speech remained significantly impaired, leading to difficulty in communication. One and a half years after the stroke, the patient was admitted to the neurological rehabilitation department of the V.M. Bekhterev Saint Petersburg Psychoneurological Research Institute. Prior to the course of treatment with vasopressin, the patient was examined using neurological and neuropsychological methods. Moderate acoustico-amnestic aphasia and mild right-sided hemiparesis were diagnosed. The patient's expressive speech was unintelligible due to a large amount of verbal substitutions see Table 3 ; . Repetition was impaired non-uniformly: impairment was present only in relation to the repetition of sound and speech series. Pronunciation was normal. Distinct difficulties occurred in attempts to name objects and related actions. Comprehension of daily activity speech was intact with impairment only in relation to complex grammatical constructions. Written speech had more significant impairment: The patient was only able to write separate words and copy simple sentences. Phonetic analysis and reading were significantly damaged. The patient's speech was impregnated with paraphasias. There was no placebo effect. The patient was administered a course of treatment with argininevasopressin: intranasal single administration of 0.1g of the neuropeptide daily for 2 months with a total dosage of 4g.

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